Two sample MR report
C1orf189_T Proliferating against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.0132766 | 0.0784946 | 0.8933315 |
| Weighted median | 3 | 0.0300845 | 0.0093837 | 0.0013457 |
| Inverse variance weighted | 3 | 0.0310575 | 0.0072566 | 0.0000187 |
| Simple mode | 3 | 0.0300658 | 0.0100313 | 0.0956206 |
| Weighted mode | 3 | 0.0300658 | 0.0103252 | 0.1004762 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0000102 | 1 | 0.9974515 |
| Inverse variance weighted | 0.0517653 | 2 | 0.9744494 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0308575 | 0.135639 | 0.8575944 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.95e-05 | 0 | TRUE | 0.6116423 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
